Dr. Adams
11-26-2010, 04:45 PM
"The relationship between depression and diabetes appears to be bidirectional, suggesting diabetes increases the risk for depression and vice versa. After controlling for other risk factors for mood disorders, women with diabetes were 29% more likely to develop depression. Women who took insulin for diabetes had a further increased risk — 53% higher than women without diabetes. All associations were independent of sociodemographic, diet, and lifestyle factors.
The results also showed that compared with their nondiabetic counterparts, women with diabetes were more likely to have a higher body mass index and less likely to be physically active, a finding that suggests these 2 risk factors could be "major mediating factors."
Nevertheless, they note the association remained significant after controlling for body mass index and lifestyle factors, which suggests "depression has effects on incident diabetes independent of adiposity and inactivity."
The finding that women taking antidepressant medications were at higher risk of developing type 2 diabetes compared with those with severe depressive symptoms or physician-diagnosed depression has at least 2 possible explanations — antidepressant medications may be a marker of more severe, chronic, or recurrent depression or the medications themselves may increase diabetes risk."
Arch Intern Med. 2010;170:1884-1891.
The results also showed that compared with their nondiabetic counterparts, women with diabetes were more likely to have a higher body mass index and less likely to be physically active, a finding that suggests these 2 risk factors could be "major mediating factors."
Nevertheless, they note the association remained significant after controlling for body mass index and lifestyle factors, which suggests "depression has effects on incident diabetes independent of adiposity and inactivity."
The finding that women taking antidepressant medications were at higher risk of developing type 2 diabetes compared with those with severe depressive symptoms or physician-diagnosed depression has at least 2 possible explanations — antidepressant medications may be a marker of more severe, chronic, or recurrent depression or the medications themselves may increase diabetes risk."
Arch Intern Med. 2010;170:1884-1891.