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Atlanta Medical Psychology
The clinical practice of Dr. David B. Adams is located in The Medical Quarters in the northside of Atlanta at the junction of Scottish Rite, Northside and Saint Joseph's Hospitals. Dr. Adams consults to occupational medicine, surgeons, nurse case managers, insurers and employers regarding the psychological impact of work-related injury and the role of psychological factors in short- and long-term disability. 

 

PAST QUESTIONS OF THE WEEK

July 29, 2002

Q "My wife and I have been married for five years. She was diagnosed with manic-depression (sic) a year ago and is on a lot of medication. What is the biggest risk of this disease?"

A Adults with bipolar disorder are at high risk of completed suicide in their early 30s, usually within 7 to 12 years of the onset of the mental illness. Research shows that bipolar individuals have a 25% to 60% likelihood of attempting suicide at some point in their lives.

The investigators found that those who committed suicide were more likely to have had a first-degree family member who had also committed suicide. They were also more likely to have made more than one previous suicide attempt in the past 7 years.

The most vulnerable times for suicide were two years following a hospital admission, 7 to 12 years after the onset of the disease, and before age 35.

J Clin Psych 2002;63:469-476.

 

June 24, 2002

Q "I have been diagnosed with fibromyalgia. My doctor believes that there are psychological reasons for some of my complaints. This offends me. Why would she say that?"

A From a recent study: "Functional magnetic resonance imaging (fMRI) and neuroendocrine studies of people with fibromyalgia reinforce the notion that altered responses to pain and exercise are physiologically based (not psychological).

Fibromyalgia patients reported pain at about half the level of pressure that caused the same feelings of pain among the healthy controls.

The findings suggest that something is awry with the way the central nervous system processes painful stimuli in fibromyalgia patients, resulting in a lowered pain threshold.

Patients with fibromyalgia have an increased hypothalamic somatostatin tone. They would like to see if long-term treatment with pyridostigmine would improve growth hormone production in fibromyalgia.

While behavioral factors likely play a role in symptom expression in many of these patients, resulting in poor role functioning, the commentators note that this phenomenon is similar for all rheumatic diseases."

Arthritis Rheum 2002;46:1136-1138,1333-1350.

June 17, 2002

Q "My sister was diagnosed as paranoid schizophrenia when she was a teenager. She is now 35. She has easily had 15-20 hospital stays. All were less than three weeks, and she is only briefly better. This is very hard on the family. We were wondering if perhaps they discharge her too soon."

A Severely mentally ill patients may be less likely to be readmitted if they are hospitalized for 6 months or longer rather than shorter periods of time, according to a recent study.

The researchers compared the recidivism rates among patients who stayed in mental institutions for different periods of time.

Short-term hospital stays were defined as those that lasted between 2 days and 4 months, while long-term stays were defined as those lasting 6 months to several years. In the current study, patients in long-term care had an average of six prior hospitalizations, in contrast to an average of less than one among the short-term group.

Patients who are admitted to long-term units of a mental institution are normally more ill than those who enter short-term facilities. However, the investigators found that only 12% of long-term residents needed to re-enter the hospital during the year following discharge, less than half the recidivism rate seen among patients discharged from short-term programs.

The recidivism rate among the long-term care patients is one of the lowest published 1-year recidivism rates in any other group of patients discharged from mental institutions, the authors note.

In addition to less recidivism, the researchers found that patients who had already tried short-term facilities stayed out of the hospital longer after being discharged from long-term care than when they had previously left short-term care.

Patients admitted to long-term care can enter classes that deal with issues such as anger management and substance abuse, which are not available to short-term enrollees. Different medication regimens can also be evaluated better in a long-term unit.

June 10, 2002

Q "My husband is in anger management counseling (sic) because he has beaten me a dozen or so times. I am worried about him. What can I do?"

A "Determining whether female patients have been physically or sexually abused by an intimate partner can provide important insights into the causes of presenting symptoms, according to a recent report.

Previous reports indicate that women who are victims of domestic violence experience health problems even after the abuse has stopped... longer-term signs of abuse, such as illnesses associated with domestic violence, are not well defined.

Women who had been abused were at increased risk for health problems such as headaches, back pain, sexually transmitted diseases, vaginal bleeding and urinary tract infections, the findings indicate.

Overall, women who suffered from intimate partner violence were up to 70% more likely than their non-abused peers to experience gynecological, central nervous system and stress-related problems.

...abused women had a 60% higher rate of all health problems compared with their peers who had not been abused and a 42% higher rate of gynecological problems. Women who had been sexually abused were more likely to report at least three gynecological problems, compared with women who had been physically abused and non-abused women.

Similarly, sexually abused women were more likely to report a chronic stress-related problem such as loss of appetite and abdominal pain, compared with physically abused women and those who were not abused."

Arch Intern Med 2002;162:1157-1163.

June 3, 2002

Q "My boyfriend has rage reactions. They are getting worse. I fear him, and I told him that he has a personality disorder or some impulse disorder. Are there any current findings on a biological cause?"

A Borderline Personality Disorder and an Impulse Control Disorder may describe the problem, but there are, indeed, new findings suggesting a brain control problem:

"Scientists have tied dysfunction in a particular brain region to a psychiatric disorder marked by uncontrolled aggression. The current findings extend the link that has been reported between the orbital/medial prefrontal cortex circuit (OMPCC) and impulsive aggression.... studied 24 patients diagnosed with intermittent explosive disorder (IED). Considered an impulse-control disorder, IED is marked by outbursts of anger that far outweigh the provocation and that lead to aggressive or destructive acts.

For one, IED patients showed marked differences from other study participants in tests of "emotion recognition." For example, IED patients were more likely to perceive "neutral" facial expressions as "disgusted" and "disgusted" expressions as "angry."

... IED patients failed to stop making "disadvantageous" choices over time in a standard gambling task. According to the researchers, this is similar to patients' everyday situations in which they react to problems with aggression, despite the possible consequences.

When asked to gauge emotions in photos of people's faces, IED patients showed problems in recognizing "anger," "disgust" and "surprise."

Finally, in a test of sensory perceptions related to OMPCC function, IED patients had more difficulty identifying various odors in "scratch-and-sniff" samples.

All of this suggests that dysfunction in the OMPCC is involved in IED... individuals with other psychiatric disorders that involve impulsive behavior--such as antisocial personality disorder and obsessive/compulsive disorder--show deficits similar to those found in this study..."

Proc Nat Acad Sci 2002; May 28th Early Edition:00-00.
 

May 27, 2002

Q "My niece has twice "accidentally" injured her? Once she severely cut her arm and once she fell from an open window. She has two children, and her husband left her a few months ago. Are these really accidents?"

A "Up to 70% of all nonfatal, self-inflicted injuries treated in hospital emergency rooms were the result of failed suicide attempts. A study by the US Centers for Disease Control and Prevention revealed 158,466 of the estimated 264,108 people who visited emergency rooms for self-inflicted poisoning, cuts, gunshot wounds and other injuries in 2000 had likely tried to commit suicide.

Another 27,294 emergency room cases stemmed from possible suicide attempts, according to the report, which was based on extrapolated data collected from 66 hospitals across the nation.

Suicide is the eighth leading cause of death in the United States and the second leading cause of death for people 25 to 34 years of age. About 29,000 of the 650,000 suicide attempts each year in the US are successful.

In the CDC study, adolescents between the ages of 15 and 19 years, and young adults 20 to 34 years of age accounted for 59% of the nonfatal, self-inflicted injuries reported by the hospitals. Women made up about 57% of the injuries.

Surveys have shown 50% to 75% of Americans know someone who has committed suicide. Researchers also have noted an increase in suicide attempts, especially among young people, following media coverage of suicides by celebrities.

Recommendations include encouraging the creation of suicide prevention programs in schools, the workplace, prisons and nursing homes."

May 20, 2002

Q "My daughter was involved in a car accident in which one of her passengers was killed. Will she develop posttraumatic stress disorder?"

A "People who experience problems sleeping shortly after a traumatic event may be at risk for post-traumatic stress disorder (PTSD)...The current findings indicate that survivors of motor vehicle crashes who developed insomnia and reported excessive fatigue beginning 1 week after their accident were more likely to be diagnosed with PTSD 1 year later.

The findings suggest that diagnosing and treating sleep problems early on may help accident survivors...

(In one study) Furthermore, individuals who later developed PTSD had more severe sleep problems than patients who did not develop PTSD.

"These results suggest that on the basis of sleep complaints it is possible to detect subjects who will later develop PTSD as early as 1 month after the trauma," the researchers conclude.

Am J Psychiatry 2002;159:855-857.


May 13, 2002

Q "My cousin is autistic as is a great uncle. My sister is pregnant and I heard that complications in pregnancy cause autism. Is that accurate?"

A From a recent article: "An increased rate of minor birth and pregnancy complications appears to accompany familial factors associated with autism. This indicates that that minor pregnancy complications are not a risk factor for sporadic cases of autism.

Children diagnosed with pervasive developmental delay had significantly more obstetric risk factors than did their unaffected siblings. However, more complications were found in unaffected children with a higher degree of family loading for the broader autism phenotype.

The researchers say these findings indicate that pregnancy and birth complications are not a direct cause of autism, as a higher rate of complications would be expected in cases without a positive family history of autism.

Although this kind of study doesn't exclude severe complications playing a role, it does suggest that clinicians have to be cautious in overinterpreting minor complications. These children are probably at higher risk for complications because they develop differently in utero."

J Am Acad Child Adolesc Psychiatry 2002;41:572-579.

May 6, 2002

Q "My mother is in her 70s, and since my father died, she has been pretty depressed. I am worried because I know this depression will shorten her life."

A Not necessarily. A recent study indicated that elderly women with subthreshold depression tend to live longer than those without depression

Depression was assessed with a modified version of the Center for Epidemiologic Studies-Depression Scale (CES-D), which included 20 questions regarding particular emotions experienced during the previous week. A score of 6 to 8 was defined as subthreshold depression.

Among the women, subthreshold depression was significantly negatively related to 3- to 4-year mortality. Among the men, subthreshold depression was not associated with mortality.

A low subclinical level of depression in women "may lead to adaptive activities that are in some ways protective of health."

Am J Geriatr Psychiatry 2002;10:283-291.

April 29, 2002

Q "I am a 29 year old pregnant woman. I am also depressed, but I hear that I cannot take antidepressants. What are my options?"

A Most importantly, you should be seeking professional advice in your community and determining the cause, course and treatment for your depression. Antidepressant use during pregnancy is controversial, and there have been few treatment options for the 5% of pregnant women who meet criteria for major depression. These women may respond to bright light therapy in the morning, according to results of an open trial published in the April issue of the American Journal of Psychiatry.

For 3 to 5 weeks, 16 pregnant patients with major depression received bright light therapy for 1 hour after awakening in the morning and showed no evidence of adverse effects. On the Hamilton Depression Rating Scale, Seasonal Affective Disorders Version, mean depression ratings improved by 49% after 3 weeks of treatment and by 59% in the 7 patients who had 5 weeks of treatment.

Some data suggest that light therapy advances the timing of the daily biological clock, which may then bring about the antidepressant effect.

Am J Psychiatry.2002;159(4):666-669

April 15, 2002

Q "I use St. John's Wart (sic) for the treatment of my depression. I think it works better for me than Zoloft which was prescribed before...any recent articles about this?"

A In an 8-week, randomized trial reported in the April 10 issue of The Journal of the American Medical Association, St. John's wort was no better than placebo in the treatment of major depression, and sertraline was better only on a secondary outcome measure. A second study and an editorial in the same issue of the journal stress the importance of placebo controls in trials of antidepressants.
Major depression is treatable, but this research suggests that major depression of at least moderate severity should not be treated with St. John's wort,.

Neither St. John's wort nor sertraline proved to be more effective than placebo on primary measures of effectiveness St. John's wort and other herbal remedies can adversely interact with prescription medications, including antiretroviral therapy, certain cardiovascular drugs, and immunosuppressants.

A National Depressive and Manic-Depressive Association Consensus Statement on the use of placebo in clinical trials of mood disorders, published in the March issue of the Archives of General Psychiatry, concluded that findings of equivalence between a new drug and standard treatment are not evidence of efficacy unless the new drug is also significantly more effective than placebo.

JAMA. 2002;287(14):1807-1814, 1840-1847, 1853-1854

April 8, 2002

Q "I heard that a few drinks a night is actually good for me, but everyone tells me that if I drink daily I am an alcoholic. Can you point me towards an article?"

A Cutting one's alcohol intake can have health benefits. Habitual heavy drinkers who cut their alcohol intake in half for just 3 weeks experienced a drop in both blood pressure and heart rate.

In the reduced alcohol group, the men cut their intake to about 19 milliliters (mL) of ethanol a day, which is roughly one beer (18 mL of ethanol) or less than one glass of sake (27 mL of ethanol).

During the alcohol restriction period, the participants had a drop in daytime systolic blood pressure of about four points, the authors note. The men's diastolic blood pressure did not change during the reduced drinking periods, the report indicates.

Heart rates were lower also when the men cut alcohol intake, dropping by four beats per minute during the daytime and seven beats per minute at night, as reported in the March issue of the American Journal of Hypertension.

Studies have suggested that light-to-moderate alcohol consumption protects against heart disease. For most people who consume no more than 30 mL of ethanol per day (about one to two drinks per day), no changes seem necessary." Those who consume more than 30 mL of ethanol a day may want to cut back on consumption, the researcher added.

Men should restrict their drinking to 30 mL or less [of ethanol] throughout their lives to prevent alcohol-related diseases.

Am J Hypertens 2002;15:125-129.

April 1, 2002

Q "My wife is pregnant, smokes and drinks. This is our first child. I assure her that this is risky and can harm the baby. Can you point me toward an article she can read?"

A Pregnant women who drink alcohol and smoke may more than double their child's risk of developing attention-deficit/hyperactivity disorder (ADHD), according to a new report.

The investigators found that, compared with non-ADHD subjects, children diagnosed with ADHD were 2.1 times more likely to have been exposed to cigarettes and 2.5 times more likely to have been exposed to alcohol in utero.

Previous studies have found similar associations. The researchers point out that environmental exposure to alcohol and tobacco smoke may combine with pre-existing genetic factors to increase a child's ADHD risk, and suggest more research on the matter is needed.

J Am Acad Child Adolesc Psychiatry 2002;41:378-385.
 

 

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