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Atlanta Medical Psychology
The clinical practice of Dr. David B. Adams is located in The Medical Quarters in the northside of Atlanta at the junction of Scottish Rite, Northside and Saint Joseph's Hospitals. Dr. Adams consults to occupational medicine, surgeons, nurse case managers, insurers and employers regarding the psychological impact of work-related injury and the role of psychological factors in short- and long-term disability. 

 

PAST QUESTIONS OF THE WEEK

September 30, 2002

Q "My daughter was caught using Ecstasy, and he defense was "well this is no different than your having a drink."  Are there any studies that show that this drug is worse than having an occasional glass of wine."

A Yes, there are. In animal studies, striatal dopaminergic deficits are apparent following administration of MDMA ("ecstasy") in doses akin to those commonly used by individuals participating in all-night dance parties, researchers at Johns Hopkins report. Doses of 2 mg/kg of MDMA used in their studies, delivered two or three times at 3-hour intervals, were lower than those sometimes used by party-goers. The investigators suggest that recreational MDMA users may be increasing their risk for such disorders as parkinsonism.

Of five monkeys and five baboons treated, one of each died within hours because of malignant hyperthermia. One of each species also became unstable after the second dose and so they were given no more.

In the three spiders monkeys that tolerated treatment well, examination 2 weeks later revealed reduced levels of regional brain serotonin, 5-hydroxyindoleacetic acid and serotonin transporter. The fourth surviving monkey was similarly examined 6 weeks after treatment, and it was found that the three markers were reduced by 37%, 48% and 40%, respectively, compared with levels in saline-treated control animals.

These "severe, long-lasting decrements" were similarly observed in the baboons.

Whether their findings extend to humans is unknown. It may be that taking multiple doses in a night, known as "stacking," is required for dopaminergic neurotoxicity to occur.

Earlier this month, US health officials reported that the number of Americans using MDMA went up 25% between 2000 and 2001.

Science 2002;297:2260-2263.

September 23, 2002

Q "My family doctor put me on antidepressants. I took them for three weeks, felt strange while taking them, and stopped. I am still depressed, and this obviously did not cure me."

A In  JAMA 2002;288:1403-1409.: "Ineffective patient-physician communication may be largely responsible for patients' discontinuation or switching of antidepressants before completion of the recommended treatment period, according to newly published study findings.

The primary endpoints were treatment discontinuation or medication switching within three months of starting SSRI therapy.

Seventy-two percent of physicians reported that they told their patients that SSRIs must be taken for at least six months. However, only 34% of patients reported being told this and 56% said that they had received no instructions. Nine percent reported being told to take their medication for less than six months.

Compared with patients who reported being told to take their medication for at least 6 months, those who reported being told to take their medication for less than 6 months were more than three times as likely to discontinue therapy.

Treatment discontinuation was less likely when the adverse effects of the drug were discussed with the patient. However, switching medications was more common when the adverse effects were discussed, the authors note.

Other factors associated with treatment discontinuation included less than three follow-up visits for depression, the occurrence of adverse effects, and lack of a therapeutic response.

September 16, 2002

Q "My teenage son is in treatment for depression. He takes medication and is in psychotherapy. He is gaining a lot of weight, and his psychologist says that it is not likely from the medication."

A This article may be helpful: "Adolescents with depression are at increased risk for the development and persistence of obesity.

Body mass index goes up incrementally as depression worsens. If you treat depression in adolescents you may stave off the onset of obesity or prevent an obese child from becoming more obese.

The serotonin pathway or altered functioning of the hypothalamus-pituitary-adrenal axis share neurobiological mechanisms between obesity and depression. For example, Bupropion (BuSpar) treatment was effective against weight gain in adults.

Pediatrics 2002;109:497-504.

September 9, 2002

Q "My daughter was diagnosed with asthma as a child. She is now grown and was diagnosed with panic attacks last year. Is there a relationship between the two....the symptoms seem so similar."

A You might find the following of interest:

Asthmatics and people with chronic bronchitis or other respiratory diseases may be at increased risk for panic attacks--or vice versa--recent study findings suggest.

The investigators found that adults who reported having asthma, chronic bronchitis or emphysema were more likely than others (odds ratio 1.7) to experience panic attacks. For adults with other types of lung disease, the odds ratio was 2.3 for panic attacks.

Furthermore, for those who reported having some type of respiratory disease and another lung disorder, the odds ratio for panic attacks was 4.1.

These findings remained true even after controlling for other mental disorders, physical problems, and demographic characteristics, the investigators state.

Chest 2002;122;645-650.

September 2, 2002

Q "Our parents always told us that a sour outlook on life would turn against us and make us physically sick. Was this just an "ol' wives' tale"?

A Patients classified as pessimistic after completing a personality assessment have poorer self-reported physical health and mental functioning 30 years later, compared with patients classified as optimistic, Mayo Clinic researchers report.

In previous work, the researchers had found that those with an optimistic explanatory style had a 50% reduced risk of death over a 30-year period compared with patients with a mixed explanatory style.

They add that knowledge of patients' explanatory style may help healthcare providers understand patients who are prone to noncompliance with treatment regimens, have excess health care utilization, and report lower patient satisfaction with health care episodes.

Mayo Clin Proc 2002;77:748-753.

August 26, 2002

Q "My aunt recently died from cancer. She was in agony. As a family we talked many times about how needless her suffering had been. Does anyone even study why we do not permit assisted suicide or investigate why people request it?"

A In a study of Oregon nurses and social workers who care for hospice patients, control issues were among the most important reasons why patients requested physician-assisted suicide, according to a new report. In contrast, depression, lack of social support, and fear of draining the family's financial resources were among the least important reasons given. With the passing of the Death with Dignity Act in 1997, physician-assisted suicide became legal in Oregon. From 1998 to 2001, 91 individuals died by assisted suicide.

Eighty-two patients had received prescriptions for lethal medications from 1997 to 2001, the report indicates. Nearly all of the nurses who were presented with a suicide request discussed it with a coworker and 77% of the requests were discussed at an interdisciplinary conference.

Reasons rated as very important for seeking assisted suicide included a desire to control the circumstances of death, a readiness for death, and a desire to die at home, the authors note. A fear of burdening others was rated as somewhat important, but only 11% of respondents reported that family caregivers of suicide-requesting patients were more burdened than caregivers of other hospice residents.

N Engl J Med 2002;347:582-588.

August 19, 2002

Q "You do not read much about burnout among doctors?"

A About one in five US physicians are dissatisfied with their career, but this figure varies by specialty and geographic location, recent study findings indicate. For example, physicians practicing geriatric internal medicine, neonatal-perinatal medicine or pediatrics, and dermatology reported high levels of career satisfaction.

Less satisfied with their career were doctors specializing in otolaryngology, obstetrics-gynecology, ophthalmology, orthopedics and internal medicine.

Physicians practicing in New England or in west north Central states, such as Minnesota, Iowa, Missouri, North Dakota, South Dakota and Kansas, were more satisfied than those in other parts of the country.

The relatively high dissatisfaction among obstetrician/gynecologists may be "related to rising expectations for perfect birth outcomes and high medicolegal risk, in contrast, has frequently been considered one of the most attractive specialties because of its "controllable lifestyle" and "relatively narrow focus," according to the report.

"A high percentage of young physicians are very satisfied and an even higher percentage of physicians aged 65 and older report being very satisfied," the authors state. "This may be owing to the enthusiasm and idealism of youth and self-selection among the elderly. Physicians who do not retire by age 65 years probably derive considerable satisfaction from their jobs."

Physicians who reported working many hours were less likely to be satisfied with their job, while those who reported a high income--$250,000 to $299,999--were more likely to say they were very satisfied with their career, the findings indicate.

Arch Intern Med 2002;162:1577-1584.

August 12, 2002

Q "The anniversary of the terrorist attacks upon the U.S. is approaching. Has anyone studied the impact upon those in New York for example?"

A The likelihood of posttraumatic stress disorder (PTSD) following the events of September 11 was associated with direct exposure to the attacks on the World Trade Center.

Geographic proximity to the WTC crash site, time spent watching television coverage of the attacks, and the number of different kinds of potentially traumatic events participants reported seeing were significantly associated with the prevalence of probable PTSD.

The long-term consequences of these findings remain to be determined but about half of Vietnam veterans diagnosed with PTSD upon their return to the US still had the disorder 15 years later.

The prevalence was not elevated among those residing in Washington, DC, compared with other US residents. The Pentagon was not as centrally located as the World Trade Center, attenuating the reaction to its attack. It was also perceived as a military target instead of a civilian target.

In 60% of New York City households with children, the adults reported that at least one child had such symptoms as difficulty sleeping, being irritable or easily upset, or displaying separation anxiety. However, that rate was not significantly higher than those reported in other areas of the US.

As the anniversary of the terror attack approaches, researchers believe that many individuals will find their symptoms increasing.

JAMA 2002;288:581-588,633-636.  

August 5, 2002

Q "My husband and I are worried about our teenage daughter and her potential for an eating disorder. Are there any new studies regarding warning signs for which we should look?"

A In the July/August issue of the American Journal of Health Promotion, they report that while adolescent girls who participate in sports such as gymnastics are more likely than their peers to develop eating disorders, the vast majority remain healthy.

Depression, a history of sexual abuse, smoking cigarettes or marijuana, and drinking alcohol were found to be associated with a greater likelihood of having disordered eating habits.

Disordered eating habits were defined as forced vomiting, using diet pills, or taking laxatives or diuretics to lose weight in the past week.

Participation in a sport that emphasized the maintenance of a certain weight increased the risk for disordered eating by 50%. Girls who participated in these sports and reported disordered eating were also more likely to smoke, drink alcohol or use drugs, have attempted suicide, have reported a history of sexual abuse, or feel that they did not communicate well with family members.

However, most girls involved in these sports, who did not have an eating disorder, were less likely to smoke marijuana and report symptoms of depression.

The study shows that overall, sports that emphasize weight maintenance can benefit girls; but participation in these sports, coupled with specific risk factors, may make some girls more vulnerable to unhealthy eating habits.

Am J Health Prom 2002;16:341-344.

July 15, 2002

Q "Does anyone do research regarding men's diseases...like how men cope with heart attacks or prostate cancer?"

A This article may interest you: "Men faced with a diagnosis of prostate cancer appear to fare much worse emotionally if their personal coping style is one of denial and avoidance, new study findings suggest.

While much is known about the psychological impact of a cancer diagnosis, the effect a person's coping strategy has on the emotional distress caused by such a diagnosis is less clear, according to researchers.

In general, there was no relationship between reduced stress and so-called "active" coping styles like "facing the situation and accepting it," or "having a fighting spirit." In contrast, so-called avoidant behavior was more likely to lead to an increase in stress with regard to the diagnosis of prostate cancer.

"This study found that the more avoidant men are when coping with difficulty--denying or disengaging--the more difficulty they are likely to have when facing a prostate cancer diagnosis...In other words, greater use of avoidant coping as a general tendency is likely to cause greater distress when facing a prostate cancer diagnosis, regardless of the results of the diagnosis." Cancer 2002;94:2923-2929.

July 8, 2002

Q "I heard that people living in the country were more likely to commit suicide than those in the city. That seems illogical since there are more stressors in the city."

A A recent article indicates that" "Men in rural areas are increasingly more likely to commit suicide than their urban counterparts. Altogether, the suicide rate decreased by about 0.46% annually from 1970 to 1997 among men in the most urban areas, but reportedly increased by 1.08% annually among men in rural areas.

For women, suicide rates were higher in urban areas than in rural areas from 1970 to 1989. But the gap narrowed over time, such that the 52% lower risk among the most rural women in 1970 to 1974 had dropped to 16% by 1985 to 1989, and by 1995-1997, women in rural areas had a 55% higher suicide rate than women in the most urban areas.

Some of the factors that might explain the higher suicide rate in rural areas may be the greater access to firearms, physical and social isolation, and the greater social disruption during the past three decades, such as the excess number of deaths in comparison to births.

Also, "social and public policies that emphasize investment in social integration or social capital through job creation, provision of gainful employment and social services, and improved social support and networks through community organization and involvement especially for the rural youth and elderly may lower suicide rates."

Am J Public Health 2002;92:1161-1167.

July 1, 2002

Q "Our daughter has been treated repeatedly for anorexia. We have had her in many clinics. She does well for awhile and then relapses. Are there any new treatment approaches being tried?"

A There is an interesting article which suggests that: Most patients with anorexia or bulimia nervosa who participate in a computer-aided feedback program, combined with rest and limited physical activity, achieve sustained remission, Swedish researchers report in the Proceedings of the National Academy of Sciences early online edition for June 24-28.

For patients in the treatment group, one of the daily meals was eaten from a plate placed on a scale, which is connected to a computer. At regular intervals, the computer prompts the patients to record their level of satiety by manipulating a mouse button. The computer stores the satiety rating, and this yields a curve of satiety.

The patients are then asked to follow curves of eating rate and satiety that were generated by normal people. In this way patients relearn how to eat and how to feel satiated.

After each meal patients rested in a warm room for 1 hour. In addition, during treatment, anorexic patients were confined to wheelchairs or allowed to walk only slowly in the clinic. Bulimic patients were allowed to walk slowly for 30 minutes per day accompanied by a staff member. Physical restrictions were reduced during treatment and eliminated on remission, the researchers note.

PNAS (USA), June 24-28, 2002.

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